| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Genk | 30 | 21 | 5 | 4 | 69 | 30 | +39 | 68 |
| 2 | Union Saint-Gi… | 30 | 20 | 5 | 5 | 61 | 36 | +25 | 65 |
| 3 | Antwerp | 30 | 18 | 6 | 6 | 53 | 25 | +28 | 60 |
| 4 | Gent | 30 | 15 | 6 | 9 | 56 | 34 | +22 | 51 |
| 5 | Club Brugge | 30 | 13 | 10 | 7 | 49 | 36 | +13 | 49 |
| 6 | Westerlo | 30 | 14 | 6 | 10 | 58 | 49 | +9 | 48 |
| 7 | Standard Liège | 30 | 13 | 7 | 10 | 48 | 40 | +8 | 46 |
| 8 | Anderlecht | 30 | 12 | 6 | 12 | 44 | 38 | +6 | 42 |
| 9 | Charleroi | 29 | 12 | 5 | 12 | 36 | 38 | -2 | 41 |
| 10 | Cercle Brugge | 30 | 10 | 11 | 9 | 41 | 41 | +0 | 41 |
| 11 | Oud-Heverlee Leuven | 30 | 10 | 9 | 11 | 44 | 43 | +1 | 39 |
| 12 | Sint-Truidense VV | 30 | 10 | 9 | 11 | 30 | 34 | -4 | 39 |
| 13 | Mechelen | 29 | 9 | 6 | 14 | 39 | 53 | -14 | 33 |
| 14 | Kortrijk | 30 | 8 | 6 | 16 | 35 | 54 | -19 | 30 |
| 15 | AS Eupen | 30 | 7 | 6 | 17 | 39 | 62 | -23 | 27 |
| 16 | KV Oostende | 30 | 6 | 6 | 18 | 34 | 63 | -29 | 24 |
| 17 | Zulte Waregem | 30 | 5 | 9 | 16 | 41 | 69 | -28 | 24 |
| 18 | RFC Seraing | 30 | 5 | 4 | 21 | 26 | 58 | -32 | 19 |
Fixtures
| November 12, 2022 | ||
| Charleroi | 7:45 PM | Mechelen |
| March 31, 2023 | ||
| Zulte Waregem | 5:45 PM | Antwerp |
| April 1, 2023 | ||
| Cercle Brugge | 1:00 PM | Kortrijk |
| RFC Seraing | 3:15 PM | Gent |
| Westerlo | 3:15 PM | Charleroi |
| KV Oostende | 5:45 PM | Standard Liège |
| April 2, 2023 | ||
| Genk | 10:30 AM | Oud-Heverlee Leuven |
| AS Eupen | 1:00 PM | Anderlecht |
| Mechelen | 3:30 PM | Club Brugge |
| Union Saint-Gi… | 4:15 PM | Sint-Truidense VV |
| April 7, 2023 | ||
| Club Brugge | 5:45 PM | RFC Seraing |
| April 8, 2023 | ||
| Oud-Heverlee Leuven | 1:00 PM | Mechelen |
| Kortrijk | 1:00 PM | AS Eupen |
| Charleroi | 3:15 PM | Zulte Waregem |
| Gent | 5:45 PM | Union Saint-Gi… |
| April 9, 2023 | ||
| Anderlecht | 10:30 AM | Westerlo |
| Antwerp | 1:00 PM | Cercle Brugge |
| Standard Liège | 3:30 PM | Genk |
| Sint-Truidense VV | 4:15 PM | KV Oostende |
| April 14, 2023 | ||
| Standard Liège | 5:45 PM | Charleroi |
Results
| March 19, 2023 | ||
| Gent | 3 - 0 | AS Eupen |
| Union Saint-Gi… | 2 - 1 | Mechelen |
| Oud-Heverlee Leuven | 0 - 2 | Anderlecht |
| Antwerp | 0 - 1 | Charleroi |
| March 18, 2023 | ||
| Standard Liège | 2 - 2 | Zulte Waregem |
| KV Oostende | 1 - 2 | Westerlo |
| Sint-Truidense VV | 2 - 1 | RFC Seraing |
| Kortrijk | 1 - 0 | Club Brugge |
| March 17, 2023 | ||
| Cercle Brugge | 1 - 1 | Genk |
| March 12, 2023 | ||
| Anderlecht | 2 - 0 | Cercle Brugge |
| Genk | 1 - 2 | Union Saint-Gi… |
| Zulte Waregem | 2 - 6 | Gent |
| Club Brugge | 2 - 0 | Standard Liège |
| March 11, 2023 | ||
| RFC Seraing | 0 - 2 | Antwerp |
| Westerlo | 3 - 1 | Kortrijk |
| AS Eupen | 4 - 4 | KV Oostende |
| Mechelen | 1 - 0 | Sint-Truidense VV |
| March 10, 2023 | ||
| Charleroi | 0 - 1 | Oud-Heverlee Leuven |